response surface experimentation - definição. O que é response surface experimentation. Significado, conceito
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O que (quem) é response surface experimentation - definição

SEQUENTIAL EXPERIMENTATION FOR IMPROVEMENT AND FOR FINDING AN OPTIMAL RESPONSE
Response surface; Response Surface Methodology; Response surface methods; Response surfaces; Response-surface methodology; Box-Wilson method
  • Designed experiments with full factorial design (left), response surface with second-degree polynomial (right)

Response surface methodology         
In statistics, response surface methodology (RSM) explores the relationships between several explanatory variables and one or more response variables. The method was introduced by George E.
Self-experimentation in medicine         
  • Dr. [[Herta Oberheuser]] being sentenced at Nuremberg
  • Karl Landsteiner in Stockholm, 1930
  • Jesse Lazear
  • Max von Pettenkofer
  • Nicholas Senn
  • Rosalyn Yalow at the Bronx [[VA Hospital]] in 1977
  • Alexander Hoekstra self-administering an experimental, intranasal COVID-19 vaccine developed by [[Rapid Deployment Vaccine Collaborative]] in 2020.
  • Joseph Barcroft
  • Stapp being brought to a sudden stop in the rocket sled
  • Werner Forssmann
PRACTICE OF RESEARCHERS TRYING PROCEDURES ON THEMSELVES
Self-experimentation with drugs
Self-experimentation refers to scientific experimentation in which the experimenter conducts the experiment on themself. Often this means that the designer, operator, subject, analyst, and user or reporter of the experiment are all the same.
Tropical cyclone response         
  • alt=A photograph of two men walking on a flooded street towards a group of men in rafts in the background
  • alt=Photograph of the inside of a cargo jet, containing people in military field uniforms, equipment, and trucks
DISASTER RESPONSE AFTER A HURRICANE
Draft:Hurricane response; Hurricane response
Hurricane response is the disaster response after a hurricane. This response encompasses assessment and repairs to buildings and infrastructure, removal of debris, and providing public health services.

Wikipédia

Response surface methodology

In statistics, response surface methodology (RSM) explores the relationships between several explanatory variables and one or more response variables. The method was introduced by George E. P. Box and K. B. Wilson in 1951. The main idea of RSM is to use a sequence of designed experiments to obtain an optimal response. Box and Wilson suggest using a second-degree polynomial model to do this. They acknowledge that this model is only an approximation, but they use it because such a model is easy to estimate and apply, even when little is known about the process.

Statistical approaches such as RSM can be employed to maximize the production of a special substance by optimization of operational factors. Of late, for formulation optimization, the RSM, using proper design of experiments (DoE), has become extensively used. In contrast to conventional methods, the interaction among process variables can be determined by statistical techniques.